Time to Pause and Reflect

During my early career as an Urgent Care Physician, I worked in busy, under-served, and rural Urgent Care Centers (UCCs). At that time, Point-of-Care Ultrasound (POCUS) was not popular. I practiced in high acuity UC settings, where we would often have US machine and US tech during business hours with an on-call tech after hours, as well as CT scan, STAT labs, and IV placement capabilities. However, I was interested in learning more about POCUS – so I attended a few CME courses that taught MSK and soft tissue, led by companies like Sonosite.

After these courses, I returned to work excited and attempted to convince my medical director to incorporate POCUS into our UC workflow. My idea was rejected. As time passed and I moved to other jobs, I would again ask at each new urgent care clinic and would be met with the same response. They claimed it is cost-prohibitive and that training providers would be cumbersome.

The basic skills I learned from these courses withered away from lack of practice shortly after finishing these 2-day seminars. Years passed by, and I forgot about POCUS, having felt discouraged following many unsuccessful attempts to integrate it into my practice.

Yet, over the past 5 years, I have noticed a shift in the operation of UCCs nationwide. There has been a tendency to eliminate US and CT from UC, reserving it for emergency department (ED) patients and scheduled outpatient orders. Our UCC still maintained STAT labs and IV placement capabilities, but this shift created bigger problems. Mainly, it led to increases in unnecessary ED transfers, which led to longer ED wait times, unsatisfied patients, more UC bounce-backs, and delayed patient care. At the same time, the shortage of primary care providers (PCPs) continued to grow, and the wait to get timely appointments with their PCP remained difficult, resulting in many patients not receiving the care they needed.

When I first started practicing UC Medicine, the goal of many UCCs was to reduce ED burden through managing stable patients while at the same time reducing primary care burnout by offering primary care services to bridge the gap in access to care. Nonetheless, the lack of imaging in the UCCs has caused the urgent care world to fall short of these goals – including duplicate and incomplete workups and increased costs to patients (particularly when labs are ordered only to discover the need to go to the ED to finish the workup). Add on top of this the fact that many insurance companies will not pay for 2 visits on the same day and the lack of consistent X-ray staffing due to shortages, and it becomes clear that there is a dire need for POCUS and POCUS-trained providers in our UCCs.

Two years ago, I decided to dedicate my time to learning and practicing POCUS. Recently, I decided to do a fellowship in POCUS. I wanted to refine my skills to provide the best care for my patients. Many patients come in with presentations such as undifferentiated dyspnea. Is it CHF? Pneumonia? COPD? POCUS can help with medical decision-making and finalize safe disposition to the ED or home.

What about that popliteal DVT that you strongly suspect on your shift? It is 7:00 pm on a Friday night, and outpatient imaging will not be able to get your patient in until the following week. How would you handle this situation? Unfortunately, many times patients must go to the ED and sit for many hours to get a DVT study done. Or what about the early-pregnancy patient that comes in with some vaginal bleeding and pelvic pain? Is it an intrauterine pregnancy (IUP) or a miscarriage?

POCUS helps you treat each of these patients with clinical accuracy and speed. For example, one day in our clinic, we had no x-ray tech on shift. I didn’t want to ask the patient to travel, as they, like many in our patient population, have difficulty finding affordable and timely transport. Instead, I was able to diagnose a fracture and treat it using my hand-held ultrasound.

Another time, I was able to diagnose a shoulder dislocation and do postreduction imaging to confirm placement. I’ve been able to rule out cardiac tamponade on a young patient with chest pain and pericarditis on EKG and send him home safely. POCUS enabled me to see a foreign body inside an abscess I would have missed. The list of what POCUS has enabled me to diagnose and treat goes on: a right lower quadrant mass on a patient with suspected appendicitis, with expedited care as the ED saw these images and took him straight to CT scan; several Pneumonias on the ultrasound that were missed on chest x-ray; the ability to differentiate between biliary colic and acute cholecystitis while doing a right upper quadrant scan.

One day, a colleague came and asked me if I could do a Renal Ultrasound on her patient, an elderly female who had been seen in the ED the day before with flank pain and hematuria. She received a CT scan in the ED showing moderate hydronephrosis and a partially obstructed ureteric stone. She came to the UC 24 hours later with worsening flank pain and vomiting. My bedside POCUS showed severe hydronephrosis and a completely obstructed ureteric calculus, with the added advantage of ruling out abdominal aortic aneurysm (AAA) at the same time. We were able to transfer her to the ED and expedite her care.

I offer all of these examples to showcase POCUS’s diverse breadth and depth in urgent care medicine. Undoubtedly, it saves lives, improves patient outcomes, and reduces costs. It is time to take a step back and consider the long-term benefits of POCUS.

The money spent now on machines and training will pay dividends in the future. While it seems like a longer-term investment, it will be recouped quickly, and the benefits will continue year after year.

Amera Gaballa, MD, is an Advanced Primary Care Ultrasound Fellow at the University of Michigan in Ann Arbor.

Fetal Neurosonography

A call for increased awareness and training within the United States

Routine evaluation of the fetal brain is performed during the second-trimester anatomical survey. This screening is conducted by transabdominal scan in 3 axial planes, namely, the transventricular, transthalamic, and transcerebellar planes.1 Targeted neurosonography, however, is a dedicated, detailed, and diagnostic examination of the fetal brain that is preferably performed with high-resolution transvaginal ultrasound via a transfontanelle approach, providing multiplanar assessment of the brain anatomy. Like fetal echocardiography in the context of suspected cardiac malformation, neurosonography provides greater diagnostic capacity for fetal brain malformations compared to the routine transabdominal screen in the axial planes.

Neurosonography involves extensive evaluation in multiple successive coronal planes (Figure 1), the midsagittal/median plane (Figure 2), as well as successive parasagittal planes (side to side) to provide high-resolution imaging of detailed brain anatomy. These include structures such as the cavum septi pellucidy and cavum vergae, corpus callosum, vermis, 3rd and 4th ventricles, vein of Gallen, ganglionic eminence, the caudate nuclei and brain stem, the fetal brain cortex, gyration, sulcation, and parenchyma as well as detailed evaluation of the entire ventricular system and periventricular tissue.2

Figure 1: 3D tomographic display of successive coronal planes from the front to the back of the fetal brain. The top left box displays the midsagittal plane with several successive lines, each representing a coronal slice displayed in the following boxes.
Figure 2A–C: Midsagittal/median plane of a 21-week fetus obtained via transfontanelle approach. Detailed evaluation of the midline structures (A) with arrows to identify some important landmarks (B). Color high definition used to depict the course of the anterior cerebral artery and the pericallosal artery (C). Bs indicates brain stem; cc, corpus callosum; csp, cavum septi pellucidi; cm, cysterna magna; cv, cavum vergae; qc, quadrigeminal cistern; qp, quadrigeminal plate; tc, tela choroidea; V, vermis; 3v, third ventricle; 4v, fourth ventricle.

The use of 3D ultrasound is also frequently utilized to facilitate expert neurosonographic evaluation, obtain the diagnostic planes, and use display modalities, which may further enable the diagnostic process.3 This technique has been used to adequately diagnose multiple fetal brain pathologies including birth defects, fetal infections, brain tumors, vascular insults, AV malformations, and destructive lesions.

Given that the anatomy of the fetal brain evolves and changes throughout gestation, correlation of the anatomy to the gestational age is a key element required by experts in neurosonography. Thus, different pathologies in the development of the fetal brain can be appropriately detected at different gestational ages. For example, whereas a major malformation such as alobar holoprosencephaly can be reliably detected in the first trimester, most abnormalities of the corpus callosum and cerebellar vermis are reliably diagnosed during the second-trimester scan, while malformations of cortical development, migrational disorders, and some tumors and destructive lesions may not be appropriately detected until the third trimester.

Despite its great diagnostic strength, fetal neurosonography is not commonly practiced in the US. Most providers who provide fetal anatomy scans are not adequately trained to perform transvaginal transfontanelle brain scans, interpret fetal brain images in the nontraditional axial planes (such as the coronal and sagittal planes), or correlate these images with the evolution of the brain anatomy throughout the different gestational ages. Therefore, in some centers, the mere suspicion of a fetal brain malformation may result in immediate referral for a fetal MRI. Although MRI is a complementary method to image the fetal brain that in expert hands may provide valuable information to neurosonography, it is a second-line imaging modality, which is far more expensive and less accessible. Importantly, like neurosonography, fetal MRI is also highly operator-dependent, requiring a high level of expertise in both obtaining the appropriate sequences as well as interpreting the images and correlating them with the gestational age. Moreover, the value of fetal MRI increases in the third trimester when evaluation of the cortex and parenchyma is feasible, whereas neurosonography provides superior images during the first- and second-trimester evaluations.4

Of note, current American guidelines for neurosonography are limited to evaluation of neonates and infants5 rather than fetuses. The most comprehensive guidelines for fetal neurosonography are published by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG).6  These guidelines also define the indications for detailed neurosonography: such as suspicion of brain malformation on routine screening ultrasound or nuchal translucency scan, family history or prior pregnancy affected by brain malformation, fetal congenital heart disease, monochorionic twins, suspected congenital intrauterine infection, exposure to teratogens affecting neurogenesis, and microarray findings of unknown significance.

Not only does neurosonography facilitate accurate diagnosis of a large variety of brain malformations, it also enables us to reassure many anxious patients in which malformation was suspected on a basic scan whereas detailed neurosonography confirmed normal brain development with no pathology.

Therefore, increased awareness of the value of fetal neurosonography and appropriate utilization may result in the referral of patients with appropriate indications to centers with expertise in neurosonography, as well as highlighting the need for specific education and training. Additionally, there is no specific Current Procedural Terminology (CPT®) code for fetal neurosonography in the US. Creation of such a code will facilitate the acceptance of this practice for indicated cases and help solidify training programs and providers’ interest in becoming proficient.

References:

  1. Malinger G, Paladini D, Haratz KK, Monteagudo A, Pilu G, Timor-Tritsch IE. ISUOG Practice Guidelines (updated): sonographic examination of the fetal central nervous system. Part 1: performance of screening examination and indications for targeted neurosonography. Ultrasound Obstet Gynecol 2020; 56:476–484.
  2. Timor-Tritsch IE, Monteagudo A. Transvaginal fetal neurosonography: standardization of the planes and sections by anatomic landmarks. Ultrasound Obstet Gynecol 1996; 8:42–47.
  3. Bornstein E, Monteagudo A, Santos R, Strock I, Tsymbal T, Lenchner E, Timor-Tritsch IE. Basic as well as detailed neurosonograms can be performed by offline analysis of three-dimensional fetal brain volumes. Ultrasound Obstet Gynecol 2010 Jul; 36(1):20–25. doi: 10.1002/uog.7527. PMID: 20069671.
  4. Malinger G, Paladini D, Pilu G, Timor-Tritsch IE. Fetal cerebral magnetic resonance imaging, neurosonography and the brave new world of fetal medicine. Ultrasound Obstet Gynecol 2017; 50:679–680.
  5. AIUM practice parameter for the performance of neurosonography in neonates and infants. J Ultrasound Med 2020; 39: E57–E61. https://doi.org/10.1002/jum.15264.
  6. Paladini D, Malinger G, Birnbaum R, Monteagudo A, Pilu G, Salomon LJ, Timor IE. ISUOG practice guidelines (updated): sonographic examination of the fetal central nervous system. Part 2: performance of targeted neurosonography. Ultrasound Obstet Gynecol 2021; 57: 661–671. https://doi.org/10.1002/uog.23616.

About the Author

Eran Bornstein, MD, FACOG, is an associate professor of Obstetrics & Gynecology in the Zucker School of Medicine/HOFSTRA, and the Director of the Center for Maternal Fetal Medicine and Ultrasound in OBGYN, at Lenox Hill Hospital, Northwell, in New York.


Interested in learning more about fetal neurosonography? Check out the following articles from the American Institute of Ultrasound in Medicine’s (AIUM’s) Journal of Ultrasound in Medicine (JUM). Members of AIUM can access them for free after logging in to the AIUMJoin the AIUM today!